Stress is an event that we all experience it in our daily life, diverges into multiple human disorders. Long term\nstressful episodes may cause oxidative damage, neuroinflammation and neurotransmitter imbalance that may lead to mental\ndisorder such as anxiety, psychosis, Alzheimer�s, Parkinson�s. Consumption of nutritional diets loaded with therapeutic\nconstituents, may endow with beneficial effects and alleviating stress mediated neuropsychiatric disorders. Therefore, aim of\nour study was to screen Annona squamosa (Sugar apple) juice for its protective effect on brain. Interestingly, Annona squamosa\njuice (ASJ) has shown favorable effects on brain antioxidant biomarkers. ASJ was effective to increase the brain catalase activity\nand GSH levels, whereas reduce the MDA levels in mice. The underlying mechanism of action of ASJ appears to be a net\nconsequence of scavenging of free radicals and neuroprotective effect mediated through its phytoconstituents. Thus\nintroduction of Annona squamosa (Sugar apple) juice on regular basis in our daily diet would help in protecting us from various\nneuropsychiatric problems.
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